• accession：NM_007240
• 基因别名：DUSP12
• 基因描述：Homo sapiens dual specificity phosphatase 12 (DUSP12), mRNA.
• 载体： 现货载体
• CDS区长度：1023
• 翻译后氨基酸长度：340
• 基因简介：The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGTTGGAGGCTCCGGGCCCGAGTGATGGCTGCGAGCTCAGCAACCCCAGCGCCAGCAGAGTCAGCTGTGCCGGGCAGATGCTGGAAGTGCAGCCAGGATTGTATTTCGGTGGGGCCGCGGCCGTCGCGGAGCCAGATCACCTGAGGGAAGCGGGCATCACGGCCGTGCTAACAGTGGACTCGGAGGAGCCCAGCTTCAAGGCGGGGCCTGGGGTCGAGGATCTATGGCGCCTCTTCGTGCCAGCGCTGGACAAACCCGAGACGGACCTACTCAGCCATCTGGACCGGTGCGTGGCCTTCATCGGTCAGGCCCGCGCTGAGGGCCGTGCGGTGTTGGTGCACTGTCATGCAGGAGTCAGTCGAAGTGTGGCCATAATAACTGCTTTTCTCATGAAGACTGACCAACTTCCCTTTGAAAAAGCCTATGAAAAGCTCCAGATTCTCAAACCAGAGGCTAAGATGAATGAGGGGTTTGAGTGGCAACTGAAATTATACCAGGCAATGGGATATGAAGTGGATACCTCTAGTGCAATTTATAAGCAATATCGTTTACAAAAGGTTACAGAGAAGTATCCAGAATTGCAGAATTTACCTCAAGAACTCTTTGCTGTTGACCCAACTACCGTTTCACAAGGATTGAAAGATGAGGTTCTCTACAAGTGTAGAAAGTGCAGGCGATCATTATTTCGAAGTTCTAGTATTCTGGATCACCGTGAAGGAAGTGGACCTATAGCCTTTGCCCACAAGAGAATGACACCATCTTCCATGCTTACCACAGGGAGGCAAGCTCAATGTACATCTTATTTCATTGAACCTGTACAGTGGATGGAATCTGCTTTGTTGGGAGTGATGGATGGACAGCTTCTTTGCCCAAAATGCAGTGCCAAGTTGGGTTCCTTCAACTGGTATGGTGAACAGTGCTCTTGTGGTAGGTGGATAACACCTGCTTTTCAAATACATAAGAATAGAGTGGATGAAATGAAAATATTGCCTGTTTTGGGATCACAAACAGGAAAAATATGA

翻译后氨基酸参数序列： 点击查看序列

ATGTTGGAGGCTCCGGGCCCGAGTGATGGCTGCGAGCTCAGCAACCCCAGCGCCAGCAGAGTCAGCTGTGCCGGGCAGATGCTGGAAGTGCAGCCAGGATTGTATTTCGGTGGGGCCGCGGCCGTCGCGGAGCCAGATCACCTGAGGGAAGCGGGCATCACGGCCGTGCTAACAGTGGACTCGGAGGAGCCCAGCTTCAAGGCGGGGCCTGGGGTCGAGGATCTATGGCGCCTCTTCGTGCCAGCGCTGGACAAACCCGAGACGGACCTACTCAGCCATCTGGACCGGTGCGTGGCCTTCATCGGTCAGGCCCGCGCTGAGGGCCGTGCGGTGTTGGTGCACTGTCATGCAGGAGTCAGTCGAAGTGTGGCCATAATAACTGCTTTTCTCATGAAGACTGACCAACTTCCCTTTGAAAAAGCCTATGAAAAGCTCCAGATTCTCAAACCAGAGGCTAAGATGAATGAGGGGTTTGAGTGGCAACTGAAATTATACCAGGCAATGGGATATGAAGTGGATACCTCTAGTGCAATTTATAAGCAATATCGTTTACAAAAGGTTACAGAGAAGTATCCAGAATTGCAGAATTTACCTCAAGAACTCTTTGCTGTTGACCCAACTACCGTTTCACAAGGATTGAAAGATGAGGTTCTCTACAAGTGTAGAAAGTGCAGGCGATCATTATTTCGAAGTTCTAGTATTCTGGATCACCGTGAAGGAAGTGGACCTATAGCCTTTGCCCACAAGAGAATGACACCATCTTCCATGCTTACCACAGGGAGGCAAGCTCAATGTACATCTTATTTCATTGAACCTGTACAGTGGATGGAATCTGCTTTGTTGGGAGTGATGGATGGACAGCTTCTTTGCCCAAAATGCAGTGCCAAGTTGGGTTCCTTCAACTGGTATGGTGAACAGTGCTCTTGTGGTAGGTGGATAACACCTGCTTTTCAAATACATAAGAATAGAGTGGATGAAATGAAAATATTGCCTGTTTTGGGATCACAAACAGGAAAAATATGA