- accession:NM_133168
- 基因别名:OSCAR
- 基因描述:Homo sapiens osteoclast associated, immunoglobulin-like receptor (OSCAR), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:759
- 翻译后氨基酸长度:252
- TranscriptVariant:This variant (5) lacks two in-frame exons in the central coding region and lacks an internal segment in its 3' coding region, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1.
- 基因简介:Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
- 规格:10ul 质粒
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