- accession:NM_001159296
- 基因别名:KLF8
- 基因描述:Homo sapiens Kruppel-like factor 8 (KLF8), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:774
- 翻译后氨基酸长度:257
- TranscriptVariant:This variant (2) differs in the 5' UTR and lacks an exon in the 3' coding region that causes a frameshift compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1.
- 基因简介:This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
- 规格:10ul 质粒
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