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人 NUDT5 (NM_014142) cDNA克隆
人 NUDT5 (NM_014142) cDNA克隆
  • 商品货号:FC129826
  • 已售 6 件 | 评价 0 人次 | 关注度 400
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    • accession:NM_014142
    • 基因别名:NUDT5
    • 基因描述:Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 5 (NUDT5), mRNA.
    • 载体:现货载体
    • CDS区长度:660
    • 翻译后氨基酸长度:219
    • 基因简介:This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列