- accession:NM_001199642
- 基因别名:ADCY5
- 基因描述:Homo sapiens adenylate cyclase 5 (ADCY5), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2736
- 翻译后氨基酸长度:911
- TranscriptVariant:This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
- 基因简介:This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
- 规格:10ul 质粒
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