- accession:NM_138632
- 基因别名:TRIOBP
- 基因描述:Homo sapiens TRIO and F-actin binding protein (TRIOBP), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1296
- 翻译后氨基酸长度:431
- TranscriptVariant:This variant (2) differs in the 5' UTR, 3' UTR, and coding region (compared to variant 6), resulting in a protein that has shorter and distinct N- and C-termini when it is compared to isoform 6.
- 基因简介:This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]
- 规格:10ul 质粒
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