- accession:NM_001252274
- 基因别名:UGT2A1
- 基因描述:Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2082
- 翻译后氨基酸长度:693
- TranscriptVariant:This variant (2) contains an additional in-frame coding exon in the 5' region, and lacks an in-frame coding exon in the 3' region compared to variant 1. This results in a longer isoform (2) differing in two internal protein segments compared to isoform 1.
- 基因简介:The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- 规格:10ul 质粒
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