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人 HUWE1 (NM_031407) cDNA克隆
人 HUWE1 (NM_031407) cDNA克隆
  • 商品货号:FC128372
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    • accession:NM_031407
    • 基因别名:HUWE1
    • 基因描述:Homo sapiens HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (HUWE1), mRNA.
    • 载体:现货载体
    • CDS区长度:13125
    • 翻译后氨基酸长度:4374
    • 基因简介:This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. [provided by RefSeq, Aug 2013]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列