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- accession：NM_001015053
- 基因别名：HDAC5
- 基因描述：Homo sapiens histone deacetylase 5 (HDAC5), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：3372
- 翻译后氨基酸长度：1123
- TranscriptVariant：This variant (3) represents the longer transcript and encodes the longer isoform (3).
- 基因简介：Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
