- accession:NM_005006
- 基因别名:NDUFS1
- 基因描述:Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) (NDUFS1), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:2184
- 翻译后氨基酸长度:727
- TranscriptVariant:This variant (1) represents the longest and predominant transcript. Variant 1 encodes isoform 1.
- 基因简介:The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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