- accession:NM_005046
- 基因别名:KLK7
- 基因描述:Homo sapiens kallikrein-related peptidase 7 (KLK7), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:762
- 翻译后氨基酸长度:253
- TranscriptVariant:This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 2 encode the same isoform.
- 基因简介:This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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