- accession:NM_206828
- 基因别名:NLRP7
- 基因描述:Homo sapiens NLR family, pyrin domain containing 7 (NLRP7), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2943
- 翻译后氨基酸长度:980
- TranscriptVariant:This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 3, resulting in a shorter protein (isoform 2), compared to isoform 3.
- 基因简介:This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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