• accession：NM_004836
• 基因别名：EIF2AK3
• 基因描述：Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3), mRNA.
• 载体：现货载体
• CDS区长度：3351
• 翻译后氨基酸长度：1116
• 基因简介：The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGAGCGCGCCATCAGCCCGGGGCTGCTGGTACGGGCGCTGCTGCTGCTGCTGCTGCTGCTGGGGCTCG
CGGCAAGGACGGTGGCCGCGGGGCGCGCCCGTGGCCTCCCAGCGCCGACGGCGGAGGCGGCGTTCGGCCT
CGGGGCGGCCGCTGCTCCCACCTCAGCGACGCGAGTACCGGCGGCGGGCGCCGTGGCTGCGGCCGAGGTG
ACTGTGGAGGACGCTGAGGCGCTGCCGGCAGCCGCGGGAGAGCAGGAGCCTCGGGGTCCGGAACCAGACG
ATGAGACAGAGTTGCGACCGCGCGGCAGGTCATTAGTAATTATCAGCACTTTAGATGGGAGAATTGCTGC
CTTGGATCCTGAAAATCATGGTAAAAAGCAGTGGGATTTGGATGTGGGATCCGGTTCCTTGGTGTCATCC
AGCCTTAGCAAACCAGAGGTATTTGGGAATAAGATGATCATTCCTTCCCTGGATGGAGCCCTCTTCCAGT
GGGACCAAGACCGTGAAAGCATGGAAACAGTTCCTTTCACAGTTGAATCACTTCTTGAATCTTCTTATAA
ATTTGGAGATGATGTTGTTTTGGTTGGAGGAAAATCTCTGACTACATATGGACTCAGTGCATATAGTGGA
AAGGTGAGGTATATCTGTTCAGCTCTGGGTTGTCGCCAATGGGATAGTGACGAAATGGAACAAGAGGAAG
ACATCCTGCTTCTACAGCGTACCCAAAAAACTGTTAGAGCTGTCGGACCTCGCAGTGGCAATGAGAAGTG
GAATTTCAGTGTTGGCCACTTTGAACTTCGGTATATTCCAGACATGGAAACGAGAGCCGGATTTATTGAA
AGCACCTTTAAGCCCAATGAGAACACAGAAGAGTCTAAAATTATTTCAGATGTGGAAGAACAGGAAGCTG
CCATAATGGACATAGTGATAAAGGTTTCGGTTGCTGACTGGAAAGTTATGGCATTCAGTAAGAAGGGAGG
ACATCTGGAATGGGAGTACCAGTTTTGTACTCCAATTGCATCTGCCTGGTTACTTAAGGATGGGAAAGTC
ATTCCCATCAGTCTTTTTGATGATACAAGTTATACATCTAATGATGATGTTTTAGAAGATGAAGAAGACA
TTGTAGAAGCTGCCAGAGGAGCCACAGAAAACAGTGTTTACTTGGGAATGTATAGAGGCCAGCTGTATCT
GCAGTCATCAGTCAGAATTTCAGAAAAGTTTCCTTCAAGTCCCAAGGCTTTGGAATCTGTCACTAATGAA
AACGCAATTATTCCTTTACCAACAATCAAATGGAAACCCTTAATTCATTCTCCTTCCAGAACTCCTGTCT
TGGTAGGATCTGATGAATTTGACAAATGTCTCAGTAATGATAAGTTTTCTCATGAAGAATATAGTAATGG
TGCACTTTCAATCTTGCAGTATCCATATGATAATGGTTATTATCTACCATACTACAAGAGGGAGAGGAAC
AAACGAAGCACACAGATTACAGTCAGATTCCTCGACAACCCACATTACAACAAGAATATCCGCAAAAAGG
ATCCTGTTCTTCTTTTACACTGGTGGAAAGAAATAGTTGCAACGATTTTGTTTTGTATCATAGCAACAAC
GTTTATTGTGCGCAGGCTTTTCCATCCTCATCCTCACAGGCAAAGGAAGGAGTCTGAAACTCAGTGTCAA
ACTGAAAATAAATATGATTCTGTAAGTGGTGAAGCCAATGACAGTAGCTGGAATGACATAAAAAACTCTG
GATATATATCACGATATCTAACTGATTTTGAGCCAATTCAATGCCTGGGACGTGGTGGCTTTGGAGTTGT
TTTTGAAGCTAAAAACAAAGTAGATGACTGCAATTATGCTATCAAGAGGATCCGTCTCCCCAATAGGGAA
TTGGCTCGGGAAAAGGTAATGCGAGAAGTTAAAGCCTTAGCCAAGCTTGAACACCCGGGCATTGTTAGAT
ATTTCAATGCCTGGCTCGAAGCACCACCAGAGAAGTGGCAAGAAAAGATGGATGAAATTTGGCTGAAAGA
TGAAAGCACAGACTGGCCACTCAGCTCTCCTAGCCCAATGGATGCACCATCAGTTAAAATACGCAGAATG
GATCCTTTCGCTACAAAAGAACATATTGAAATCATAGCTCCTTCACCACAAAGAAGCAGGTCTTTTTCAG
TAGGGATTTCCTGTGACCAGACAAGTTCATCTGAGAGCCAGTTCTCACCACTGGAATTCTCAGGAATGGA
CCATGAGGACATCAGTGAGTCAGTGGATGCAGCATACAACCTCCAGGACAGTTGCCTTACAGACTGTGAT
GTGGAAGATGGGACTATGGATGGCAATGATGAGGGGCACTCCTTTGAACTTTGTCCTTCTGAAGCTTCTC
CTTATGTAAGGTCAAGGGAGAGAACCTCCTCTTCAATAGTATTTGAAGATTCTGGCTGTGATAATGCTTC
CAGTAAAGAAGAGCCGAAAACTAATCGATTGCATATTGGCAACCATTGTGCTAATAAACTAACTGCTTTC
AAGCCCACCAGTAGCAAATCTTCTTCTGAAGCTACATTGTCTATTTCTCCTCCAAGACCAACCACTTTAA
GTTTAGATCTCACTAAAAACACCACAGAAAAACTCCAGCCCAGTTCACCAAAGGTGTATCTTTACATTCA
AATGCAGCTGTGCAGAAAAGAAAACCTCAAAGACTGGATGAATGGACGATGTACCATAGAGGAGAGAGAG
AGGAGCGTGTGTCTGCACATCTTCCTGCAGATCGCAGAGGCAGTGGAGTTTCTTCACAGTAAAGGACTGA
TGCACAGGGACCTCAAGCCATCCAACATATTCTTTACAATGGATGATGTGGTCAAGGTTGGAGACTTTGG
GTTAGTGACTGCAATGGACCAGGATGAGGAAGAGCAGACGGTTCTGACCCCAATGCCAGCTTATGCCAGA
CACACAGGACAAGTAGGGACCAAACTGTATATGAGCCCAGAGCAGATTCATGGAAACAGCTATTCTCATA
AAGTGGACATCTTTTCTTTAGGCCTGATTCTATTTGAATTGCTGTATCCATTCAGCACTCAGATGGAGAG
AGTCAGGACCTTAACTGATGTAAGAAATCTCAAATTTCCACCATTATTTACTCAGAAATATCCTTGTGAG
TACGTGATGGTTCAAGACATGCTCTCTCCATCCCCCATGGAACGACCTGAAGCTATAAACATCATTGAAA
ATGCTGTATTTGAGGACTTGGACTTTCCAGGAAAAACAGTGCTCAGACAGAGGTCTCGCTCCTTGAGTTC
ATCGGGAACAAAACATTCAAGACAGTCCAACAACTCCCATAGCCCTTTGCCAAGCAATTAG

翻译后氨基酸参数序列： 点击查看序列

ATGGAGCGCGCCATCAGCCCGGGGCTGCTGGTACGGGCGCTGCTGCTGCTGCTGCTGCTGCTGGGGCTCG
CGGCAAGGACGGTGGCCGCGGGGCGCGCCCGTGGCCTCCCAGCGCCGACGGCGGAGGCGGCGTTCGGCCT
CGGGGCGGCCGCTGCTCCCACCTCAGCGACGCGAGTACCGGCGGCGGGCGCCGTGGCTGCGGCCGAGGTG
ACTGTGGAGGACGCTGAGGCGCTGCCGGCAGCCGCGGGAGAGCAGGAGCCTCGGGGTCCGGAACCAGACG
ATGAGACAGAGTTGCGACCGCGCGGCAGGTCATTAGTAATTATCAGCACTTTAGATGGGAGAATTGCTGC
CTTGGATCCTGAAAATCATGGTAAAAAGCAGTGGGATTTGGATGTGGGATCCGGTTCCTTGGTGTCATCC
AGCCTTAGCAAACCAGAGGTATTTGGGAATAAGATGATCATTCCTTCCCTGGATGGAGCCCTCTTCCAGT
GGGACCAAGACCGTGAAAGCATGGAAACAGTTCCTTTCACAGTTGAATCACTTCTTGAATCTTCTTATAA
ATTTGGAGATGATGTTGTTTTGGTTGGAGGAAAATCTCTGACTACATATGGACTCAGTGCATATAGTGGA
AAGGTGAGGTATATCTGTTCAGCTCTGGGTTGTCGCCAATGGGATAGTGACGAAATGGAACAAGAGGAAG
ACATCCTGCTTCTACAGCGTACCCAAAAAACTGTTAGAGCTGTCGGACCTCGCAGTGGCAATGAGAAGTG
GAATTTCAGTGTTGGCCACTTTGAACTTCGGTATATTCCAGACATGGAAACGAGAGCCGGATTTATTGAA
AGCACCTTTAAGCCCAATGAGAACACAGAAGAGTCTAAAATTATTTCAGATGTGGAAGAACAGGAAGCTG
CCATAATGGACATAGTGATAAAGGTTTCGGTTGCTGACTGGAAAGTTATGGCATTCAGTAAGAAGGGAGG
ACATCTGGAATGGGAGTACCAGTTTTGTACTCCAATTGCATCTGCCTGGTTACTTAAGGATGGGAAAGTC
ATTCCCATCAGTCTTTTTGATGATACAAGTTATACATCTAATGATGATGTTTTAGAAGATGAAGAAGACA
TTGTAGAAGCTGCCAGAGGAGCCACAGAAAACAGTGTTTACTTGGGAATGTATAGAGGCCAGCTGTATCT
GCAGTCATCAGTCAGAATTTCAGAAAAGTTTCCTTCAAGTCCCAAGGCTTTGGAATCTGTCACTAATGAA
AACGCAATTATTCCTTTACCAACAATCAAATGGAAACCCTTAATTCATTCTCCTTCCAGAACTCCTGTCT
TGGTAGGATCTGATGAATTTGACAAATGTCTCAGTAATGATAAGTTTTCTCATGAAGAATATAGTAATGG
TGCACTTTCAATCTTGCAGTATCCATATGATAATGGTTATTATCTACCATACTACAAGAGGGAGAGGAAC
AAACGAAGCACACAGATTACAGTCAGATTCCTCGACAACCCACATTACAACAAGAATATCCGCAAAAAGG
ATCCTGTTCTTCTTTTACACTGGTGGAAAGAAATAGTTGCAACGATTTTGTTTTGTATCATAGCAACAAC
GTTTATTGTGCGCAGGCTTTTCCATCCTCATCCTCACAGGCAAAGGAAGGAGTCTGAAACTCAGTGTCAA
ACTGAAAATAAATATGATTCTGTAAGTGGTGAAGCCAATGACAGTAGCTGGAATGACATAAAAAACTCTG
GATATATATCACGATATCTAACTGATTTTGAGCCAATTCAATGCCTGGGACGTGGTGGCTTTGGAGTTGT
TTTTGAAGCTAAAAACAAAGTAGATGACTGCAATTATGCTATCAAGAGGATCCGTCTCCCCAATAGGGAA
TTGGCTCGGGAAAAGGTAATGCGAGAAGTTAAAGCCTTAGCCAAGCTTGAACACCCGGGCATTGTTAGAT
ATTTCAATGCCTGGCTCGAAGCACCACCAGAGAAGTGGCAAGAAAAGATGGATGAAATTTGGCTGAAAGA
TGAAAGCACAGACTGGCCACTCAGCTCTCCTAGCCCAATGGATGCACCATCAGTTAAAATACGCAGAATG
GATCCTTTCGCTACAAAAGAACATATTGAAATCATAGCTCCTTCACCACAAAGAAGCAGGTCTTTTTCAG
TAGGGATTTCCTGTGACCAGACAAGTTCATCTGAGAGCCAGTTCTCACCACTGGAATTCTCAGGAATGGA
CCATGAGGACATCAGTGAGTCAGTGGATGCAGCATACAACCTCCAGGACAGTTGCCTTACAGACTGTGAT
GTGGAAGATGGGACTATGGATGGCAATGATGAGGGGCACTCCTTTGAACTTTGTCCTTCTGAAGCTTCTC
CTTATGTAAGGTCAAGGGAGAGAACCTCCTCTTCAATAGTATTTGAAGATTCTGGCTGTGATAATGCTTC
CAGTAAAGAAGAGCCGAAAACTAATCGATTGCATATTGGCAACCATTGTGCTAATAAACTAACTGCTTTC
AAGCCCACCAGTAGCAAATCTTCTTCTGAAGCTACATTGTCTATTTCTCCTCCAAGACCAACCACTTTAA
GTTTAGATCTCACTAAAAACACCACAGAAAAACTCCAGCCCAGTTCACCAAAGGTGTATCTTTACATTCA
AATGCAGCTGTGCAGAAAAGAAAACCTCAAAGACTGGATGAATGGACGATGTACCATAGAGGAGAGAGAG
AGGAGCGTGTGTCTGCACATCTTCCTGCAGATCGCAGAGGCAGTGGAGTTTCTTCACAGTAAAGGACTGA
TGCACAGGGACCTCAAGCCATCCAACATATTCTTTACAATGGATGATGTGGTCAAGGTTGGAGACTTTGG
GTTAGTGACTGCAATGGACCAGGATGAGGAAGAGCAGACGGTTCTGACCCCAATGCCAGCTTATGCCAGA
CACACAGGACAAGTAGGGACCAAACTGTATATGAGCCCAGAGCAGATTCATGGAAACAGCTATTCTCATA
AAGTGGACATCTTTTCTTTAGGCCTGATTCTATTTGAATTGCTGTATCCATTCAGCACTCAGATGGAGAG
AGTCAGGACCTTAACTGATGTAAGAAATCTCAAATTTCCACCATTATTTACTCAGAAATATCCTTGTGAG
TACGTGATGGTTCAAGACATGCTCTCTCCATCCCCCATGGAACGACCTGAAGCTATAAACATCATTGAAA
ATGCTGTATTTGAGGACTTGGACTTTCCAGGAAAAACAGTGCTCAGACAGAGGTCTCGCTCCTTGAGTTC
ATCGGGAACAAAACATTCAAGACAGTCCAACAACTCCCATAGCCCTTTGCCAAGCAATTAG