- accession:NM_001164489
- 基因别名:ADAM8
- 基因描述:Homo sapiens ADAM metallopeptidase domain 8 (ADAM8), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2229
- 翻译后氨基酸长度:742
- TranscriptVariant:This variant (2) lacks an alternate exon and uses an alternate splice site, which causes a frameshift in the 3' coding region, compared to variant 1. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 1.
- 基因简介:This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]
- 规格:10ul 质粒
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