- accession:NM_183401
- 基因别名:RNF14
- 基因描述:Homo sapiens ring finger protein 14 (RNF14), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:1425
- 翻译后氨基酸长度:474
- TranscriptVariant:This variant (5) differs in the 5' UTR compared to variant 1. Both variants encode the same isoform (1).
- 基因简介:The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
- 规格:10ul 质粒
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