- accession:NM_001204423
- 基因别名:RGS6
- 基因描述:Homo sapiens regulator of G-protein signaling 6 (RGS6), transcript variant 9, mRNA.
- 载体:现货载体
- CDS区长度:1314
- 翻译后氨基酸长度:437
- TranscriptVariant:This variant (9) differs in the 5' UTR, and is missing 2 non-consecutive exons compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (9) with a shorter N-terminus compared to isoform 1.
- 基因简介:This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
- 规格:10ul 质粒
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