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- accession：NM_001204418
- 基因别名：RGS6
- 基因描述：Homo sapiens regulator of G-protein signaling 6 (RGS6), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：1404
- 翻译后氨基酸长度：467
- TranscriptVariant：This variant (4) is missing the penultimate coding exon, and uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1. This results in a frame-shift, and a shorter isoform (4, also known as RGS6Lbeta2) with a distinct C-terminus compared to isoform 1.
- 基因简介：This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
