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- accession：NM_001206992
- 基因别名：NR1H4
- 基因描述：Homo sapiens nuclear receptor subfamily 1, group H, member 4 (NR1H4), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：1449
- 翻译后氨基酸长度：482
- TranscriptVariant：This variant (4) contains an alternate 5' terminal exon, and uses an alternate in-frame donor splice site at an internal coding exon compared to variant 1. This results in translation initiation from an alternate in-frame start codon, and a longer isoform (4, also known as FXRbeta-) with a distinct N-terminus and missing a 4 aa protein segment compared to isoform 1.
- 基因简介：This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
