- accession:NM_170771
- 基因别名:ALDH8A1
- 基因描述:Homo sapiens aldehyde dehydrogenase 8 family, member A1 (ALDH8A1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1302
- 翻译后氨基酸长度:433
- TranscriptVariant:This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment compared to isoform 1.
- 基因简介:This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
- 规格:10ul 质粒
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