- accession:NM_001269048
- 基因别名:CTCFL
- 基因描述:Homo sapiens CCCTC-binding factor (zinc finger protein)-like (CTCFL), transcript variant 10, mRNA.
- 载体:现货载体
- CDS区长度:1452
- 翻译后氨基酸长度:483
- TranscriptVariant:This variant (10, also known as C6) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. The resulting isoform (8) lacks an internal segment and has a shorter and distinct C-terminus, compared to isoform 1.
- 基因简介:CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
- 规格:10ul 质粒
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