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人 PRKCQ (NM_001242413) cDNA克隆
人 PRKCQ (NM_001242413) cDNA克隆
  • 商品货号:FC125057
  • 已售 6 件 | 评价 0 人次 | 关注度 325
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    • accession:NM_001242413
    • 基因别名:PRKCQ
    • 基因描述:Homo sapiens protein kinase C, theta (PRKCQ), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:1932
    • 翻译后氨基酸长度:643
    • TranscriptVariant:This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    • 基因简介:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列