• accession：NM_006377
• 基因别名：UNC13B
• 基因描述：Homo sapiens unc-13 homolog B (C. elegans) (UNC13B), mRNA.
• 载体：现货载体
• CDS区长度：4776
• 翻译后氨基酸长度：1591
• 基因简介：This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGTCACTGCTCTGCGTGCGCGTTAAAAGGGCCAAATTCCAGGGTTCACCAGATAAATTTAACACATATG
TGACCCTGAAAGTACAGAATGTGAAGAGCACAACTGTAGCAGTTCGTGGTGATCAGCCTTCCTGGGAACA
GGATTTCATGTTTGAGATTAGTCGCCTGGACCTGGGTCTAAGTGTGGAGGTATGGAACAAAGGACTGATC
TGGGACACCATGGTGGGGACTGTGTGGATTGCGCTGAAGACTATTCGTCAGTCGGATGAGGAAGGGCCTG
GGGAATGGTCCACATTAGAGGCAGAGACGTTAATGAAAGACGATGAGATCTGTGGAACTAGAAACCCAAC
TCCTCATAAAATTTTGCTTGATACAAGATTTGAGTTGCCTTTTGATATCCCAGAGGAGGAAGCCAGATAT
TGGACCTACAAATGGGAGCAAATCAATGCCTTGGGAGCTGACAATGAGTATTCTAGTCAAGAAGAAAGCC
AGAGGAAGCCATTGCCCACTGCTGCCGCCCAGTGTTCTTTTGAAGACCCTGATAGTGCCGTCGATGACCG
AGATAGTGACTATCGCAGTGAGACCAGCAACAGCTTCCCACCTCCTTACCATACAGCTTCCCAGCCCAAC
GCTTCTGTGCACCAGTTCCCTGTGCCGGTGCGATCGCCACAGCAGCTGCTACTTCAAGGCAGTTCCCGGG
ACTCTTGTAATGACTCTATGCAAAGTTATGACCTTGATTATCCAGAGCGGCGGGCTATCAGCCCCACCAG
CAGCAGTAGGTATGGCTCCTCCTGTAATGTGAGTCAAGGAAGCTCTCAGCTAAGTGAACTAGACCAGTAT
CACGAACAAGATGACGACCATCGGGAGACGGACTCGATTCATTCTTGCCACAGCTCTCACAGCCTGTCCA
GAGATGGCCAAGCAGGTTTTGGAGAACAAGAGAAACCCTTGGAGGTGACAGGTCAAGCAGAGAAGGAGGC
AGCATGTGAACCCAAGGAGATGAAAGAAGATGCCACAACCCACCCTCCCCCAGATCTGGTGCTGCAAAAA
GACCACTTCCTAGGTCCCCAGGAGAGTTTTCCTGAGGAGAATGCATCTTCACCATTTACCCAAGCCAGAG
CACATTGGATCCGAGCAGTTACCAAGGTTCGACTCCAGCTGCAGGAGATTCCAGATGATGGTGACCCCTC
TCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGC
AGAAAGAAGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTG
CAATGGCTACACGCACTTCTCTTAAGGACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGC
CTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCTGGACGGCCACTACCCCAACCTAC
TGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAGTCA
AGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAA
ACATGGAGCTGAGGACCGGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGA
AATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCTTCACAGTGAACAAAGCTGCCCATGTGCAGCAGA
TGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCACCATTACTGTGGT
GTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGC
AAAACTAAGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTG
AGTGCCACAACTCCTCTGACCGCATTAAGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGT
AAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCATCATTGAGGTTCGGACCCTAAGT
GGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCCGAC
TACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCA
TGAGAATCTTTTCCATTACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGA
GACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCCAAGAAATTGTGGATGAATTTGCCATGCGTTATG
GCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACATGTGTCCTGGTGT
GCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAAT
GTCTCTGCATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGC
TACACAACTCACTGAGGATCGACCTCTCTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCT
TCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCTTCAGAATGAAGGTACAAGAACTG
CAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATGAAT
ATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGA
ACAAGGGCCCAGCATTCGGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAG
GAAGATAAGAATTCCTACACACCTGTTCTGAACCAGTTTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCG
CAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATGAGAAAGACCACCT
GTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGAT
CTGCCTGTCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGG
ATGAGAATGAGGATGTATCCCTGGAATTCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCA
GCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCTTCACACAACTCAATCAGAGCTTT
GAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTAAGA
CCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGA
GAAACTGCCCTGCATCCTGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCC
ATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACAGTCTGAAGGAGCTGCAGGTGAAACTGAATACGG
TTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGTGTGTTCGACAAAT
GGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAG
GATGCAGATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGT
GTGAGAAGACGGTTCTGAAGCGTGTACTGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGAT
GATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCTTCACTGCTGCCAAGGAGCTGAGC
CATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTGCAG
TCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTT
CCTGGAGAAGAGCCCAGATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACT
CTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCT
CTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGC
CAATGACCTCAAGTGGCAGACAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACAC
CAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAAGCAACAACTGGGCCCCCAAGTACAATGAGA
CATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAGTTGCAGATATGCGTGAAGGATTA
CTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTCTGAGGGATGTCACAGCCAAGGGC
AGCTGTGCCTGCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGA
TTTTATCTCAGAGGAGCAATGACGAGGTGGCCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCAC
GGAGGAGGGGAGCTGA

翻译后氨基酸参数序列： 点击查看序列

ATGTCACTGCTCTGCGTGCGCGTTAAAAGGGCCAAATTCCAGGGTTCACCAGATAAATTTAACACATATG
TGACCCTGAAAGTACAGAATGTGAAGAGCACAACTGTAGCAGTTCGTGGTGATCAGCCTTCCTGGGAACA
GGATTTCATGTTTGAGATTAGTCGCCTGGACCTGGGTCTAAGTGTGGAGGTATGGAACAAAGGACTGATC
TGGGACACCATGGTGGGGACTGTGTGGATTGCGCTGAAGACTATTCGTCAGTCGGATGAGGAAGGGCCTG
GGGAATGGTCCACATTAGAGGCAGAGACGTTAATGAAAGACGATGAGATCTGTGGAACTAGAAACCCAAC
TCCTCATAAAATTTTGCTTGATACAAGATTTGAGTTGCCTTTTGATATCCCAGAGGAGGAAGCCAGATAT
TGGACCTACAAATGGGAGCAAATCAATGCCTTGGGAGCTGACAATGAGTATTCTAGTCAAGAAGAAAGCC
AGAGGAAGCCATTGCCCACTGCTGCCGCCCAGTGTTCTTTTGAAGACCCTGATAGTGCCGTCGATGACCG
AGATAGTGACTATCGCAGTGAGACCAGCAACAGCTTCCCACCTCCTTACCATACAGCTTCCCAGCCCAAC
GCTTCTGTGCACCAGTTCCCTGTGCCGGTGCGATCGCCACAGCAGCTGCTACTTCAAGGCAGTTCCCGGG
ACTCTTGTAATGACTCTATGCAAAGTTATGACCTTGATTATCCAGAGCGGCGGGCTATCAGCCCCACCAG
CAGCAGTAGGTATGGCTCCTCCTGTAATGTGAGTCAAGGAAGCTCTCAGCTAAGTGAACTAGACCAGTAT
CACGAACAAGATGACGACCATCGGGAGACGGACTCGATTCATTCTTGCCACAGCTCTCACAGCCTGTCCA
GAGATGGCCAAGCAGGTTTTGGAGAACAAGAGAAACCCTTGGAGGTGACAGGTCAAGCAGAGAAGGAGGC
AGCATGTGAACCCAAGGAGATGAAAGAAGATGCCACAACCCACCCTCCCCCAGATCTGGTGCTGCAAAAA
GACCACTTCCTAGGTCCCCAGGAGAGTTTTCCTGAGGAGAATGCATCTTCACCATTTACCCAAGCCAGAG
CACATTGGATCCGAGCAGTTACCAAGGTTCGACTCCAGCTGCAGGAGATTCCAGATGATGGTGACCCCTC
TCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGAGGGCTCTATGGCATTGACAGCATGCCAGATTTACGC
AGAAAGAAGCCACTGCCACTTGTCAGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTG
CAATGGCTACACGCACTTCTCTTAAGGACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGC
CTTAATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCTGGACGGCCACTACCCCAACCTAC
TGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGCAGCGAATGTGGAGTCA
AGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTGCAGCGGGCTGCAGAAAAGAGCTGTAA
ACATGGAGCTGAGGACCGGACCCAGAACATTATCATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGA
AATAAGCCAGAGATCTTTGAAGTTATCCGGGACGTCTTCACAGTGAACAAAGCTGCCCATGTGCAGCAGA
TGAAAACAGTGAAGCAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCACCATTACTGTGGT
GTGTGCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAAGTCAGC
AAAACTAAGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAGGAGAAGTTCCATTTTG
AGTGCCACAACTCCTCTGACCGCATTAAGGTGCGTGTATGGGATGAGGATGATGACATCAAGTCAAGAGT
AAAGCAACGCCTAAAGCGAGAGTCTGATGATTTCCTTGGCCAAACCATCATTGAGGTTCGGACCCTAAGT
GGCGAGATGGACGTCTGGTACAACTTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCCGAC
TACAAATCAGTGTGGAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCA
TGAGAATCTTTTCCATTACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCTCGAGGA
GACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCCAAGAAATTGTGGATGAATTTGCCATGCGTTATG
GCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTATCATCCAAGTACATGTGTCCTGGTGT
GCCAGCAGTGATGAGCACCTTACTGGCCAACATCAACGCCTACTATGCCCACACAACTGCCTCTACCAAT
GTCTCTGCATCTGATCGCTTTGCAGCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGC
TACACAACTCACTGAGGATCGACCTCTCTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCT
TCAGGACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCTTCAGAATGAAGGTACAAGAACTG
CAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTGAACTCCACATATGAAT
ATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAGCTGAAGCAGGAGCTACCTCCAGAGGA
ACAAGGGCCCAGCATTCGGAACCTGGATTTCTGGCCCAAGCTCATCACACTCATCGTGTCAATCATAGAG
GAAGATAAGAATTCCTACACACCTGTTCTGAACCAGTTTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCG
CAGAAGTGATGTGGCATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATGAGAAAGACCACCT
GTGTAAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTGCGGGAT
CTGCCTGTCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTCGTGCTACAATGGCTGG
ATGAGAATGAGGATGTATCCCTGGAATTCCTGCGTGGGGCCCTGGAACGAGATAAGAAGGATGGATTCCA
GCAGACATCAGAGCATGCACTCTTTTCCTGCTCTGTGGTGGATGTCTTCACACAACTCAATCAGAGCTTT
GAGATCATCCGGAAGCTGGAATGCCCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTAAGA
CCATCGGGAAGGTGCTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGA
GAAACTGCCCTGCATCCTGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTTGAGGCC
ATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACAGTCTGAAGGAGCTGCAGGTGAAACTGAATACGG
TTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTACGGATTGATGAGTGTGTTCGACAAAT
GGCCGACATCCTGGGCCAGGTTCGGGGCACAGGGAATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAG
GATGCAGATAGCGTACTCCGGCCTCTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGT
GTGAGAAGACGGTTCTGAAGCGTGTACTGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGAT
GATTGTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCTTCACTGCTGCCAAGGAGCTGAGC
CATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACTCCAAAGCAGTGTGCAG
TCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCAGGAGGCAATGGGCTGAAGAAAACCTT
CCTGGAGAAGAGCCCAGATCTGCAGTCTCTACGCTATGCCCTGTCTCTGTACACACAGACTACTGACACT
CTCATCAAGACCTTTGTGCGCTCGCAGACCACCCAAGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCT
CTATTCAGGTGGACTTGTTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGC
CAATGACCTCAAGTGGCAGACAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCACAC
CAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAAGCAACAACTGGGCCCCCAAGTACAATGAGA
CATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAGTTGCAGATATGCGTGAAGGATTA
CTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCTGTGATGCCTCTGAGGGATGTCACAGCCAAGGGC
AGCTGTGCCTGCTGGTGCCCCTTGGGCCGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGA
TTTTATCTCAGAGGAGCAATGACGAGGTGGCCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCAC
GGAGGAGGGGAGCTGA