- accession:NM_001145370
- 基因别名:PTPN3
- 基因描述:Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:2214
- 翻译后氨基酸长度:737
- TranscriptVariant:This variant (4) differs in the 5' UTR, and is missing an in-frame coding exon compared to transcript variant 1, resulting in an isoform (4) with a shorter N-terminus and lacking an internal protein segment compared to isoform 1.
- 基因简介:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
- 规格:10ul 质粒
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