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- accession：NM_001258447
- 基因别名：TOP1MT
- 基因描述：Homo sapiens topoisomerase (DNA) I, mitochondrial (TOP1MT), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1512
- 翻译后氨基酸长度：503
- TranscriptVariant：This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 2 and 3 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
- 基因简介：This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
