- accession:NM_181524
- 基因别名:PIK3R1
- 基因描述:Homo sapiens phosphoinositide-3-kinase, regulatory subunit 1 (alpha) (PIK3R1), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:1275
- 翻译后氨基酸长度:424
- TranscriptVariant:This variant (3) uses an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (3) has a distinct N-terminus, compared to isoform 1.
- 基因简介:Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- 规格:10ul 质粒
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