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人 TREM1 (NM_001242590) cDNA克隆
人 TREM1 (NM_001242590) cDNA克隆
  • 商品货号:FC120824
  • 已售 3 件 | 评价 0 人次 | 关注度 336
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    • accession:NM_001242590
    • 基因别名:TREM1
    • 基因描述:Homo sapiens triggering receptor expressed on myeloid cells 1 (TREM1), transcript variant 3, mRNA.
    • 载体:现货载体
    • CDS区长度:453
    • 翻译后氨基酸长度:150
    • TranscriptVariant:This variant (3) is missing an internal coding exon compared to variant 1. This results in a frame-shift, and a shorter isoform (3) with a distinct C-terminus compared to isoform 1. This isoform, lacking the transmembrane domain, is likely secreted, and may function as a regulator of myeloid activation (PMID:11922939).
    • 基因简介:This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列