• 商品货号：F106658

• accession：NM_002803
• 基因别名：PSMC2
• 基因描述：Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), transcript variant 1, mRNA.
• 载体： 现货载体
• CDS区长度：1302
• 翻译后氨基酸长度：433
• TranscriptVariant：This variant (1) represents the longer transcript and encodes the longer isoform (1).
• 基因简介：The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGCCGGATTACCTCGGTGCCGATCAGCGGAAGACCAAAGAGGATGAGAAGGACGACAAGCCCATCCGAGCTCTGGATGAGGGGGATATTGCCTTGTTGAAAACTTATGGTCAGAGCACTTACTCTAGGCAGATCAAGCAAGTTGAAGATGACATTCAGCAACTTCTCAAGAAAATTAATGAGCTCACTGGTATTAAAGAATCTGACACTGGCCTGGCCCCACCAGCACTCTGGGATTTGGCTGCAGATAAGCAGACACTCCAGAGTGAACAGCCTTTACAGGTTGCCAGGTGTACAAAGATAATCAATGCTGATTCGGAGGACCCAAAATACATTATCAACGTAAAGCAGTTTGCCAAGTTTGTGGTGGACCTTAGTGATCAGGTGGCACCTACTGACATTGAAGAAGGGATGAGAGTGGGCGTGGATAGAAATAAATATCAAATTCACATTCCATTGCCTCCTAAGATTGACCCAACAGTTACCATGATGCAGGTGGAAGAGAAACCTGATGTCACATACAGTGATGTTGGTGGCTGTAAGGAACAGATTGAGAAACTGCGAGAAGTAGTTGAAACCCCATTACTTCATCCAGAGAGGTTTGTGAACCTTGGCATTGAGCCTCCCAAGGGCGTGCTGCTCTTTGGTCCACCCGGTACAGGCAAGACACTCTGTGCGCGGGCAGTTGCTAATCGGACTGATGCGTGCTTCATTCGAGTTATTGGATCTGAGCTTGTACAGAAATACGTCGGTGAGGGGGCTCGAATGGTTCGTGAACTCTTTGAAATGGCCAGAACAAAAAAAGCCTGCCTTATCTTCTTTGATGAAATTGATGCTATTGGAGGGGCTCGTTTTGATGATGGTGCTGGAGGTGACAATGAAGTGCAGAGAACAATGTTGGAACTGATCAATCAGCTTGATGGTTTTGATCCTCGAGGCAATATTAAAGTGCTGATGGCCACTAACAGACCTGATACTTTGGATCCAGCACTGATGAGGCCAGGGAGATTGGATAGAAAAATTGAATTTAGCTTGCCCGATCTAGAGGGTCGGACCCACATATTTAAGATTCACGCTCGTTCAATGAGTGTTGAAAGAGATATCAGATTTGAACTGTTAGCACGACTGTGTCCAAATAGCACTGGTGCTGAGATTAGAAGCGTCTGCACAGAGGCTGGTATGTTTGCCATCAGAGCACGGCGAAAAATTGCTACCGAGAAGGATTTCTTGGAAGCTGTAAATAAGGTCATTAAGTCTTATGCCAAATTCAGTGCTACTCCTCGTTACATGACATACAACTGA

翻译后氨基酸参数序列： 点击查看序列

ATGCCGGATTACCTCGGTGCCGATCAGCGGAAGACCAAAGAGGATGAGAAGGACGACAAGCCCATCCGAGCTCTGGATGAGGGGGATATTGCCTTGTTGAAAACTTATGGTCAGAGCACTTACTCTAGGCAGATCAAGCAAGTTGAAGATGACATTCAGCAACTTCTCAAGAAAATTAATGAGCTCACTGGTATTAAAGAATCTGACACTGGCCTGGCCCCACCAGCACTCTGGGATTTGGCTGCAGATAAGCAGACACTCCAGAGTGAACAGCCTTTACAGGTTGCCAGGTGTACAAAGATAATCAATGCTGATTCGGAGGACCCAAAATACATTATCAACGTAAAGCAGTTTGCCAAGTTTGTGGTGGACCTTAGTGATCAGGTGGCACCTACTGACATTGAAGAAGGGATGAGAGTGGGCGTGGATAGAAATAAATATCAAATTCACATTCCATTGCCTCCTAAGATTGACCCAACAGTTACCATGATGCAGGTGGAAGAGAAACCTGATGTCACATACAGTGATGTTGGTGGCTGTAAGGAACAGATTGAGAAACTGCGAGAAGTAGTTGAAACCCCATTACTTCATCCAGAGAGGTTTGTGAACCTTGGCATTGAGCCTCCCAAGGGCGTGCTGCTCTTTGGTCCACCCGGTACAGGCAAGACACTCTGTGCGCGGGCAGTTGCTAATCGGACTGATGCGTGCTTCATTCGAGTTATTGGATCTGAGCTTGTACAGAAATACGTCGGTGAGGGGGCTCGAATGGTTCGTGAACTCTTTGAAATGGCCAGAACAAAAAAAGCCTGCCTTATCTTCTTTGATGAAATTGATGCTATTGGAGGGGCTCGTTTTGATGATGGTGCTGGAGGTGACAATGAAGTGCAGAGAACAATGTTGGAACTGATCAATCAGCTTGATGGTTTTGATCCTCGAGGCAATATTAAAGTGCTGATGGCCACTAACAGACCTGATACTTTGGATCCAGCACTGATGAGGCCAGGGAGATTGGATAGAAAAATTGAATTTAGCTTGCCCGATCTAGAGGGTCGGACCCACATATTTAAGATTCACGCTCGTTCAATGAGTGTTGAAAGAGATATCAGATTTGAACTGTTAGCACGACTGTGTCCAAATAGCACTGGTGCTGAGATTAGAAGCGTCTGCACAGAGGCTGGTATGTTTGCCATCAGAGCACGGCGAAAAATTGCTACCGAGAAGGATTTCTTGGAAGCTGTAAATAAGGTCATTAAGTCTTATGCCAAATTCAGTGCTACTCCTCGTTACATGACATACAACTGA