×
![]()
- accession：NM_001083592
- 基因别名：ROR1
- 基因描述：Homo sapiens receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1182
- 翻译后氨基酸长度：393
- TranscriptVariant：This variant (2) contains a distinct 3' UTR and lacks an in-frame portion of the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter C-terminus that lacks a tyrosine kinase catalytic domain, compared to isoform 1.
- 基因简介：This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
