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- accession：NM_203472
- 基因别名：VIMP
- 基因描述：Homo sapiens VCP-interacting membrane protein (VIMP), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：564
- 翻译后氨基酸长度：187
- TranscriptVariant：This variant (1) represents the longer transcript. It lacks a portion of the 3' UTR structure and therefore excises the Sec Insertion Sequence necessary for recoding of selenocysteines. This results in a protein (isoform 1) which uses an earlier stop codon and contains a shorter C-terminus, compared to isoform 2.
- 基因简介：This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
