• accession：NM_014780
• 基因别名：CUL7
• 基因描述：Homo sapiens cullin 7 (CUL7), transcript variant 2, mRNA.
• 载体：现货载体
• CDS区长度：5097
• 翻译后氨基酸长度：1698
• TranscriptVariant：This variant (2) uses alternate splice junctions at the 3' end of two different exons compared to variant 1. One alternate splice junction causes a frameshift compared to variant 1 while the other does not. The resulting isoform (2) has a longer N-terminus and contains an alternate segment compared to isoform 1.
• 基因简介：The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGTGGGAGAACTCCGCTACAGGGAATTCAGGGTGCCCCTGGGGCCCGGCTTACATGCCTATCCTGATG
AGCTGATCCGCCAGCGCGTGGGCCATGATGGGCATCCTGAGTACCAGATCCGTTGGCTCATCCTGCGGCG
TGGCGATGAGGGGGACGGGGGCTCTGGCCAAGTGGACTGCAAGGCTGAGCACATCCTGCTGTGGATGTCC
AAGGATGAGATCTATGCCAACTGCCACAAGATGCTGGGCGAGGATGGCCAGGTCATCGGGCCCTCCCAGG
AGTCTGCAGGGGAGGTTGGGGCCCTGGACAAATCTGTGCTGGAGGAGATGGAAACCGACGTGAAGTCCCT
CATTCAGAGAGCCCTTCGGCAGCTGGAGGAGTGTGTGGGCACTATCCCTCCTGCTCCTCTACTTCACACT
GTCCACGTGCTCAGCGCCTATGCCAGCATTGAGCCCCTCACTGGAGTATTCAAGGACCCAAGGGTCCTGG
ACTTGCTCATGCACATGTTGAGTAGTCCTGATTATCAGATTCGCTGGAGTGCAGGCCGGATGATACAAGC
CCTGTCCTCCCATGACGCTGGGACCCGGACTCAGATCCTTCTGTCACTGAGCCAACAAGAAGCCATTGAG
AAACACCTGGATTTTGACAGCCGCTGTGCTCTGCTAGCACTGTTTGCACAGGCCACGCTCTCTGAACACC
CCATGTCTTTCGAGGGCATTCAGCTACCACAGGTCCCAGGAAGGGTGCTCTTCTCCCTGGTGAAGCGGTA
TTTGCATGTCACCTCGCTCCTGGATCAGCTGAACGACAGTGCTGCGGAGCCAGGAGCCCAGAACACCTCT
GCTCCTGAGGAGTTGAGTGGGGAGAGGGGTCAACTGGAGCTGGAGTTCAGTATGGCCATGGGCACCCTGA
TCTCGGAGCTGGTGCAAGCCATGCGCTGGGACCAGGCCTCAGACAGACCAAGGAGCTCAGCACGGTCCCC
CGGTTCCATCTTCCAGCCTCAGCTGGCAGATGTGAGCCCAGGGCTCCCCGCTGCCCAGGCTCAGCCCTCC
TTCAGGAGGTCAAGACGTTTTCGCCCTCGTTCTGAGTTCGCAAGTGGCAATACCTATGCTTTGTATGTGC
GGGACACACTGCAGCCGGGGATGCGAGTGCGGATGCTGGATGATTATGAGGAGATCAGTGCCGGGGATGA
GGGCGAGTTTCGGCAGAGCAACAACGGTGTGCCTCCTGTGCAGGTATTTTGGGAGTCAACAGGCCGCACC
TATTGGGTGCACTGGCACATGCTGGAGATCTTGGGCTTTGAGGAAGACATTGAGGACATGGTTGAGGCTG
ATGAGTACCAAGGGGCAGTGGCCAGTAGAGTCCTGGGTAGAGCCCTGCCTGCCTGGCGCTGGAGGCCCAT
GACAGAACTCTATGCTGTGCCTTATGTGCTGCCTGAGGATGAGGACACTGAGGAGTGTGAACACCTGACC
CTGGCTGAGTGGTGGGAACTCCTCTTCTTCATCAAGAAGCTGGATGGACCTGACCATCAGGAGGTTCTCC
AGATCCTCCAGGAGAACCTAGATGGGGAGATTCTGGATGATGAGATCCTAGCTGAACTGGCCGTGCCCAT
AGAATTGGCCCAGGACTTGCTGCTGACTCTGCCACAGCGACTCAATGACAGTGCCCTCAGGGACCTGATC
AACTGCCATGTCTACAAGAAGTATGGGCCTGAAGCCCTAGCAGGGAACCAAGCCTACCCATCCCTTCTAG
AAGCCCAAGAAGATGTCCTCCTGCTAGACGCGCAGGCCCAGGCTAAGGACTCAGAAGATGCAGCCAAAGT
GGAAGCAAAAGAACCCCCATCTCAGAGTCCCAACACTCCCCTGCAGCGTCTGGTGGAGGGTTATGGTCCA
GCTGGGAAAATCCTCCTGGATCTAGAGCAAGCCCTCAGCTCAGAGGGGACCCAGGAGAACAAGGTCAAGC
CACTCCTGCTGCAGCTGCAGCGGCAGCCGCAGCCCTTCCTGGCACTGATGCAGAGCCTGGACACTCCGGA
GACTAACAGGACCCTGCACCTGACTGTGCTGAGAATCCTGAAGCAGCTGGTGGACTTCCCCGAGGCACTG
CTGCTCCCCTGGCACGAGGCCGTGGATGCCTGCATGGCCTGCCTGCGGTCCCCAAACACTGATCGAGAGG
TGCTCCAGGAACTGATTTTCTTCCTGCACCGCCTGACCTCAGTGAGCAGGGACTATGCCGTGGTGCTGAA
TCAGCTGGGAGCAAGAGACGCTATCTCCAAGGCCCTGGAAAAGCACCTGGGAAAGCTGGAGCTGGCTCAG
GAGCTGCGGGACATGGTGTTCAAGTGTGAGAAGCATGCCCACCTCTACCGCAAACTCATCACCAACATCC
TGGGAGGCTGCATCCAGATGGTGCTGGGCCAGATCGAAGACCACAGACGAACCCACCAACCCATCAACAT
CCCTTTCTTTGATGTGTTCCTCAGATACCTGTGCCAGGGCTCCAGTGTGGAAGTGAAGGAGGACAAGTGC
TGGGAGAAGGTGGAGGTGTCCTCCAACCCGCACCGGGCCAGCAAGCTGACGGACCACAACCCCAAGACCT
ATTGGGAGTCCAACGGCAGCGCCGGCTCCCACTACATCACCCTGCACATGCGCCGGGGCATCCTCATCAG
GCAACTGACTCTGCTTGTGGCTAGTGAGGACTCGAGTTACATGCCGGCCCGAGTGGTGGTGTGCGGGGGT
GATAGCACTAGCTCTCTTCACACGGAACTCAACTCGGTGAATGTGATGCCCTCTGCCAGCCGGGTGATCC
TCCTGGAGAACCTGACCCGCTTCTGGCCCATCATCCAGATCCGCATAAAGCGCTGCCAGCAGGGTGGCAT
TGATACGCGCATTCGGGGGTTAGAGATCCTAGGCCCCAAGCCCACGTTCTGGCCAGTGTTCCGGGAGCAG
CTCTGTCGTCACACACGCCTCTTCTACATGGTTCGGGCACAGGCCTGGAGCCAGGACATGGCAGAGGACC
GCAGGAGCCTCCTGCACCTGAGTTCTAGACTCAACGGTGCTCTGCGCCAGGAGCAGAATTTTGCTGACCG
CTTCCTCCCTGATGACGAGGCTGCCCAAGCTCTGGGCAAGACCTGCTGGGAGGCCCTGGTCAGCCCCGTG
GTGCAGAACATCACCTCCCCTGATGAGGATGGCATTAGCCCCCTGGGTTGGCTGCTGGACCAGTACCTGG
AGTGTCAGGAAGCTGTCTTCAACCCCCAGAGCCGCGGCCCAGCTTTCTTCTCGCGGGTGCGCCGTCTCAC
TCACCTGCTGGTGCATGTCGAGCCCTGTGAGGCACCCCCTCCTGTGGTGGCCACTCCTCGGCCCAAAGGC
AGAAACAGAAGCCACGACTGGAGCTCCTTGGCTACCCGGGGCCTTCCAAGCAGCATCATGAGAAACCTGA
CGCGCTGTTGGCGGGCCGTGGTGGAGAAGCAGGTGAACAATTTTCTGACCTCATCCTGGCGGGATGATGA
CTTTGTGCCACGCTACTGTGAGCACTTTAATATTCTGCAGAACTCAAGCTCTGAACTGTTTGGGCCTCGG
GCAGCCTTCTTGCTGGCGCTGCAAAATGGCTGTGCGGGAGCCTTGCTGAAGCTCCCTTTTCTCAAAGCTG
CCCACGTGAGTGAGCAGTTCGCCCGGCACATTGACCAGCAGATCCAGGGCAGCCGGATCGGTGGAGCCCA
GGAAATGGAGAGGCTGGCACAGCTGCAGCAATGCCTGCAAGCTGTCCTGATTTTCTCCGGCTTGGAGATA
GCCACCACTTTTGAGCATTATTACCAGCACTACATGGCGGACCGTCTCCTGGGCGTGGTCTCGAGCTGGC
TGGAGGGGGCCGTGCTGGAGCAGATCGGTCCCTGCTTCCCCAACCGCCTCCCCCAGCAGATGTTGCAGAG
CCTGAGCACCTCTAAGGAGCTGCAGCGCCAGTTCCACGTCTACCAGCTCCAGCAGCTGGATCAGGAACTC
CTGAAGCTGGAGGATACAGAGAAGAAAATACAGGTGGGCCTTGGGGCCAGTGGCAAGGAGCACAAGAGCG
AGAAGGAAGAGGAAGCTGGGGCAGCAGCAGTGGTGGATGTGGCGGAGGGAGAGGAGGAAGAGGAGGAGAA
TGAGGACCTCTACTATGAAGGGGCAATGCCAGAAGTGTCTGTGCTTGTCCTGTCCCGACACTCCTGGCCT
GTTGCCTCAATCTGCCACACACTGAACCCCAGAACCTGCCTGCCCTCCTACCTGAGGGGCACTTTGAACA
GATACTCCAACTTCTACAACAAGAGTCAGAGCCACCCTGCCCTTGAGCGAGGCTCACAGAGGCGACTGCA
GTGGACGTGGCTGGGCTGGGCTGAGCTGCAGTTTGGGAACCAGACCCTGCATGTGTCCACCGTGCAGATG
TGGCTACTGCTGTATCTCAACGACCTGAAGGCGGTCTCTGTGGAGAGTCTGCTGGCGTTCTCAGGGCTCT
CCGCAGACATGCTCAATCAGGCGATTGGGCCCCTCACCTCTTCAAGAGGCCCCCTGGACCTTCACGAGCA
AAAGGATATACCAGGAGGGGTCCTCAAGATTCGAGATGGCAGCAAGGAACCCAGGTCGAGATGGGACATT
GTGCGGCTCATCCCACCTCAGACGTACCTGCAAGCTGAGGGTGAAGACGGCCAGAACTTGGAGAAGAGAC
GGAATCTTCTGAACTGCCTCATCGTCCGAATCCTCAAGGCCCATGGAGATGAGGGGCTGCACATTGACCA
GCTTGTCTGTCTGGTGCTGGAGGCTTGGCAGAAGGGCCCGTGTCCTCCCAGGGGTTTGGTCAGCAGCCTT
GGTAAGGGGTCTGCATGCAGCAGCACTGACGTCCTCTCCTGCATCCTACACCTCCTGGGCAAGGGCACGC
TGAGACGCCATGACGACCGGCCCCAGGTGCTGTCCTATGCAGTCCCTGTGACTGTCATGGAGCCTCACAC
TGAGTCCCTGAACCCAGGCTCCTCAGGCCCCAACCCACCCCTCACCTTCCATACCCTACAGATTCGCTCC
CGGGGTGTGCCCTATGCCTCCTGCACTGCCACCCAGAGCTTCTCTACCTTCCGGTAG

翻译后氨基酸参数序列： 点击查看序列

ATGGTGGGAGAACTCCGCTACAGGGAATTCAGGGTGCCCCTGGGGCCCGGCTTACATGCCTATCCTGATG
AGCTGATCCGCCAGCGCGTGGGCCATGATGGGCATCCTGAGTACCAGATCCGTTGGCTCATCCTGCGGCG
TGGCGATGAGGGGGACGGGGGCTCTGGCCAAGTGGACTGCAAGGCTGAGCACATCCTGCTGTGGATGTCC
AAGGATGAGATCTATGCCAACTGCCACAAGATGCTGGGCGAGGATGGCCAGGTCATCGGGCCCTCCCAGG
AGTCTGCAGGGGAGGTTGGGGCCCTGGACAAATCTGTGCTGGAGGAGATGGAAACCGACGTGAAGTCCCT
CATTCAGAGAGCCCTTCGGCAGCTGGAGGAGTGTGTGGGCACTATCCCTCCTGCTCCTCTACTTCACACT
GTCCACGTGCTCAGCGCCTATGCCAGCATTGAGCCCCTCACTGGAGTATTCAAGGACCCAAGGGTCCTGG
ACTTGCTCATGCACATGTTGAGTAGTCCTGATTATCAGATTCGCTGGAGTGCAGGCCGGATGATACAAGC
CCTGTCCTCCCATGACGCTGGGACCCGGACTCAGATCCTTCTGTCACTGAGCCAACAAGAAGCCATTGAG
AAACACCTGGATTTTGACAGCCGCTGTGCTCTGCTAGCACTGTTTGCACAGGCCACGCTCTCTGAACACC
CCATGTCTTTCGAGGGCATTCAGCTACCACAGGTCCCAGGAAGGGTGCTCTTCTCCCTGGTGAAGCGGTA
TTTGCATGTCACCTCGCTCCTGGATCAGCTGAACGACAGTGCTGCGGAGCCAGGAGCCCAGAACACCTCT
GCTCCTGAGGAGTTGAGTGGGGAGAGGGGTCAACTGGAGCTGGAGTTCAGTATGGCCATGGGCACCCTGA
TCTCGGAGCTGGTGCAAGCCATGCGCTGGGACCAGGCCTCAGACAGACCAAGGAGCTCAGCACGGTCCCC
CGGTTCCATCTTCCAGCCTCAGCTGGCAGATGTGAGCCCAGGGCTCCCCGCTGCCCAGGCTCAGCCCTCC
TTCAGGAGGTCAAGACGTTTTCGCCCTCGTTCTGAGTTCGCAAGTGGCAATACCTATGCTTTGTATGTGC
GGGACACACTGCAGCCGGGGATGCGAGTGCGGATGCTGGATGATTATGAGGAGATCAGTGCCGGGGATGA
GGGCGAGTTTCGGCAGAGCAACAACGGTGTGCCTCCTGTGCAGGTATTTTGGGAGTCAACAGGCCGCACC
TATTGGGTGCACTGGCACATGCTGGAGATCTTGGGCTTTGAGGAAGACATTGAGGACATGGTTGAGGCTG
ATGAGTACCAAGGGGCAGTGGCCAGTAGAGTCCTGGGTAGAGCCCTGCCTGCCTGGCGCTGGAGGCCCAT
GACAGAACTCTATGCTGTGCCTTATGTGCTGCCTGAGGATGAGGACACTGAGGAGTGTGAACACCTGACC
CTGGCTGAGTGGTGGGAACTCCTCTTCTTCATCAAGAAGCTGGATGGACCTGACCATCAGGAGGTTCTCC
AGATCCTCCAGGAGAACCTAGATGGGGAGATTCTGGATGATGAGATCCTAGCTGAACTGGCCGTGCCCAT
AGAATTGGCCCAGGACTTGCTGCTGACTCTGCCACAGCGACTCAATGACAGTGCCCTCAGGGACCTGATC
AACTGCCATGTCTACAAGAAGTATGGGCCTGAAGCCCTAGCAGGGAACCAAGCCTACCCATCCCTTCTAG
AAGCCCAAGAAGATGTCCTCCTGCTAGACGCGCAGGCCCAGGCTAAGGACTCAGAAGATGCAGCCAAAGT
GGAAGCAAAAGAACCCCCATCTCAGAGTCCCAACACTCCCCTGCAGCGTCTGGTGGAGGGTTATGGTCCA
GCTGGGAAAATCCTCCTGGATCTAGAGCAAGCCCTCAGCTCAGAGGGGACCCAGGAGAACAAGGTCAAGC
CACTCCTGCTGCAGCTGCAGCGGCAGCCGCAGCCCTTCCTGGCACTGATGCAGAGCCTGGACACTCCGGA
GACTAACAGGACCCTGCACCTGACTGTGCTGAGAATCCTGAAGCAGCTGGTGGACTTCCCCGAGGCACTG
CTGCTCCCCTGGCACGAGGCCGTGGATGCCTGCATGGCCTGCCTGCGGTCCCCAAACACTGATCGAGAGG
TGCTCCAGGAACTGATTTTCTTCCTGCACCGCCTGACCTCAGTGAGCAGGGACTATGCCGTGGTGCTGAA
TCAGCTGGGAGCAAGAGACGCTATCTCCAAGGCCCTGGAAAAGCACCTGGGAAAGCTGGAGCTGGCTCAG
GAGCTGCGGGACATGGTGTTCAAGTGTGAGAAGCATGCCCACCTCTACCGCAAACTCATCACCAACATCC
TGGGAGGCTGCATCCAGATGGTGCTGGGCCAGATCGAAGACCACAGACGAACCCACCAACCCATCAACAT
CCCTTTCTTTGATGTGTTCCTCAGATACCTGTGCCAGGGCTCCAGTGTGGAAGTGAAGGAGGACAAGTGC
TGGGAGAAGGTGGAGGTGTCCTCCAACCCGCACCGGGCCAGCAAGCTGACGGACCACAACCCCAAGACCT
ATTGGGAGTCCAACGGCAGCGCCGGCTCCCACTACATCACCCTGCACATGCGCCGGGGCATCCTCATCAG
GCAACTGACTCTGCTTGTGGCTAGTGAGGACTCGAGTTACATGCCGGCCCGAGTGGTGGTGTGCGGGGGT
GATAGCACTAGCTCTCTTCACACGGAACTCAACTCGGTGAATGTGATGCCCTCTGCCAGCCGGGTGATCC
TCCTGGAGAACCTGACCCGCTTCTGGCCCATCATCCAGATCCGCATAAAGCGCTGCCAGCAGGGTGGCAT
TGATACGCGCATTCGGGGGTTAGAGATCCTAGGCCCCAAGCCCACGTTCTGGCCAGTGTTCCGGGAGCAG
CTCTGTCGTCACACACGCCTCTTCTACATGGTTCGGGCACAGGCCTGGAGCCAGGACATGGCAGAGGACC
GCAGGAGCCTCCTGCACCTGAGTTCTAGACTCAACGGTGCTCTGCGCCAGGAGCAGAATTTTGCTGACCG
CTTCCTCCCTGATGACGAGGCTGCCCAAGCTCTGGGCAAGACCTGCTGGGAGGCCCTGGTCAGCCCCGTG
GTGCAGAACATCACCTCCCCTGATGAGGATGGCATTAGCCCCCTGGGTTGGCTGCTGGACCAGTACCTGG
AGTGTCAGGAAGCTGTCTTCAACCCCCAGAGCCGCGGCCCAGCTTTCTTCTCGCGGGTGCGCCGTCTCAC
TCACCTGCTGGTGCATGTCGAGCCCTGTGAGGCACCCCCTCCTGTGGTGGCCACTCCTCGGCCCAAAGGC
AGAAACAGAAGCCACGACTGGAGCTCCTTGGCTACCCGGGGCCTTCCAAGCAGCATCATGAGAAACCTGA
CGCGCTGTTGGCGGGCCGTGGTGGAGAAGCAGGTGAACAATTTTCTGACCTCATCCTGGCGGGATGATGA
CTTTGTGCCACGCTACTGTGAGCACTTTAATATTCTGCAGAACTCAAGCTCTGAACTGTTTGGGCCTCGG
GCAGCCTTCTTGCTGGCGCTGCAAAATGGCTGTGCGGGAGCCTTGCTGAAGCTCCCTTTTCTCAAAGCTG
CCCACGTGAGTGAGCAGTTCGCCCGGCACATTGACCAGCAGATCCAGGGCAGCCGGATCGGTGGAGCCCA
GGAAATGGAGAGGCTGGCACAGCTGCAGCAATGCCTGCAAGCTGTCCTGATTTTCTCCGGCTTGGAGATA
GCCACCACTTTTGAGCATTATTACCAGCACTACATGGCGGACCGTCTCCTGGGCGTGGTCTCGAGCTGGC
TGGAGGGGGCCGTGCTGGAGCAGATCGGTCCCTGCTTCCCCAACCGCCTCCCCCAGCAGATGTTGCAGAG
CCTGAGCACCTCTAAGGAGCTGCAGCGCCAGTTCCACGTCTACCAGCTCCAGCAGCTGGATCAGGAACTC
CTGAAGCTGGAGGATACAGAGAAGAAAATACAGGTGGGCCTTGGGGCCAGTGGCAAGGAGCACAAGAGCG
AGAAGGAAGAGGAAGCTGGGGCAGCAGCAGTGGTGGATGTGGCGGAGGGAGAGGAGGAAGAGGAGGAGAA
TGAGGACCTCTACTATGAAGGGGCAATGCCAGAAGTGTCTGTGCTTGTCCTGTCCCGACACTCCTGGCCT
GTTGCCTCAATCTGCCACACACTGAACCCCAGAACCTGCCTGCCCTCCTACCTGAGGGGCACTTTGAACA
GATACTCCAACTTCTACAACAAGAGTCAGAGCCACCCTGCCCTTGAGCGAGGCTCACAGAGGCGACTGCA
GTGGACGTGGCTGGGCTGGGCTGAGCTGCAGTTTGGGAACCAGACCCTGCATGTGTCCACCGTGCAGATG
TGGCTACTGCTGTATCTCAACGACCTGAAGGCGGTCTCTGTGGAGAGTCTGCTGGCGTTCTCAGGGCTCT
CCGCAGACATGCTCAATCAGGCGATTGGGCCCCTCACCTCTTCAAGAGGCCCCCTGGACCTTCACGAGCA
AAAGGATATACCAGGAGGGGTCCTCAAGATTCGAGATGGCAGCAAGGAACCCAGGTCGAGATGGGACATT
GTGCGGCTCATCCCACCTCAGACGTACCTGCAAGCTGAGGGTGAAGACGGCCAGAACTTGGAGAAGAGAC
GGAATCTTCTGAACTGCCTCATCGTCCGAATCCTCAAGGCCCATGGAGATGAGGGGCTGCACATTGACCA
GCTTGTCTGTCTGGTGCTGGAGGCTTGGCAGAAGGGCCCGTGTCCTCCCAGGGGTTTGGTCAGCAGCCTT
GGTAAGGGGTCTGCATGCAGCAGCACTGACGTCCTCTCCTGCATCCTACACCTCCTGGGCAAGGGCACGC
TGAGACGCCATGACGACCGGCCCCAGGTGCTGTCCTATGCAGTCCCTGTGACTGTCATGGAGCCTCACAC
TGAGTCCCTGAACCCAGGCTCCTCAGGCCCCAACCCACCCCTCACCTTCCATACCCTACAGATTCGCTCC
CGGGGTGTGCCCTATGCCTCCTGCACTGCCACCCAGAGCTTCTCTACCTTCCGGTAG