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人FGFR1OP(NM_194429)ORF克隆
人FGFR1OP(NM_194429)ORF克隆
会员等级价V
已售 8 件 | 评价 0 人次 | 关注度 289
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  • 商品货号:F106332
  • accession:NM_194429
  • 基因别名:FGFR1OP
  • 基因描述:Homo sapiens FGFR1 oncogene partner (FGFR1OP), transcript variant 2, mRNA.
  • 载体: 现货载体
  • CDS区长度:1140
  • 翻译后氨基酸长度:379
  • TranscriptVariant:This variant (2) lacks an in-frame exon in the internal coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a.
  • 基因简介:This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列