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- accession：NM_001039920
- 基因别名：ZNF384
- 基因描述：Homo sapiens zinc finger protein 384 (ZNF384), transcript variant 6, mRNA.
- 载体：现货载体
- CDS区长度：1386
- 翻译后氨基酸长度：461
- TranscriptVariant：This variant (6) lacks two alternate in-frame exons and uses an alternate in-frame splice site in the central coding region, compared to variant 7, resulting in an isoform (c) that is shorter than isoform d.
- 基因简介：This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
