- accession:NM_001167931
- 基因别名:IL1RAP
- 基因描述:Homo sapiens interleukin 1 receptor accessory protein (IL1RAP), transcript variant 6, mRNA.
- 载体:现货载体
- CDS区长度:2064
- 翻译后氨基酸长度:687
- TranscriptVariant:This variant (6) uses an alternate 3' terminal exon, compared to variant 1. It encodes isoform 3, which has a longer and distinct C-terminus, compared to isoform 1.
- 基因简介:Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]
- 规格:10ul 质粒
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