- accession:NM_000685
- 基因别名:AGTR1
- 基因描述:Homo sapiens angiotensin II receptor, type 1 (AGTR1), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1080
- 翻译后氨基酸长度:359
- TranscriptVariant:This variant (1), also known as pC2, hAT1R-B (PubMed ID:16504375) or hAT1R-C (PubMed ID:11158334), encodes the predominant isoform (1). Variants 1 and 2 encode the same isoform 1.
- 基因简介:Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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