- accession:NM_033092
- 基因别名:TRIM5
- 基因描述:Homo sapiens tripartite motif containing 5 (TRIM5), transcript variant gamma, mRNA.
- 载体: 现货载体
- CDS区长度:1044
- 翻译后氨基酸长度:347
- TranscriptVariant:This variant (gamma) includes an alternate segment in the 3' coding region, compared to variant alpha, which results in a frameshift. The resulting protein (isoform gamma) has a shorter and distinct C-terminus, compared to isoform alpha.
- 基因简介:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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