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人 PON2 (NM_001018161) cDNA克隆
人 PON2 (NM_001018161) cDNA克隆
  • 商品货号:G116501
  • 已售 7 件 | 评价 0 人次 | 关注度 241
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    • accession:NM_001018161
    • 基因别名:PON2
    • 基因描述:Homo sapiens paraoxonase 2 (PON2), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:1029
    • 翻译后氨基酸长度:342
    • TranscriptVariant:This variant (2) uses an alternate, in-frame splice site in the coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
    • 基因简介:This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列