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- accession：NM_001039847
- 基因别名：GPX4
- 基因描述：Homo sapiens glutathione peroxidase 4 (GPX4), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：684
- 翻译后氨基酸长度：227
- TranscriptVariant：This variant (2) uses a frame-shifting alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (B) is longer and has a distinct C-terminus, compared to isoform A. Whether alternate transcription initiation sites exist in variant 2, such that two forms of isoform B are produced, needs to be experimentally verified.
- 基因简介：Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
