- 商品货号:G115249
- accession:NM_001042678
- 基因别名:RHOC
- 基因描述:Homo sapiens ras homolog family member C (RHOC), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:582
- 翻译后氨基酸长度:193
- TranscriptVariant:This variant (2) lacks an alternate exon in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same protein.
- 基因简介:This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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