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- accession：NM_000581
- 基因别名：GPX1
- 基因描述：Homo sapiens glutathione peroxidase 1 (GPX1), transcript variant 1, mRNA.
- 载体： 现货载体
- CDS区长度：612
- 翻译后氨基酸长度：203
- TranscriptVariant：This variant (1) represents the shorter transcript and encodes the longer isoform (1).
- 基因简介：This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 载体信息：自有图片地址
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
