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- 商品货号：F104742
- accession：NM_016362
- 基因别名：GHRL
- 基因描述：Homo sapiens ghrelin/obestatin prepropeptide (GHRL), transcript variant 1, mRNA.
- 载体： 现货载体
- CDS区长度：354
- 翻译后氨基酸长度：117
- TranscriptVariant：This variant (1) is generated from an alternate promoter and has a shorter 5' UTR. It encodes the longest isoform (1), which includes both the ghrelin and obestatin ligands.
- 基因简介：This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008]
- 载体信息：自有图片地址
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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