- accession:NM_138712
- 基因别名:PPARG
- 基因描述:Homo sapiens peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1434
- 翻译后氨基酸长度:477
- TranscriptVariant:This variant (1) differs in the 5' UTR and 5' coding region compared to variant 2. Variants 1, 3, and 4 encode the same isoform (1), which has a shorter, distinct N-terminus compared to isoform 2.
- 基因简介:This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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