- accession:NM_002621
- 基因别名:CFP
- 基因描述:Homo sapiens complement factor properdin (CFP), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1410
- 翻译后氨基酸长度:469
- TranscriptVariant:This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
- 基因简介:This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列