- accession:NM_001195014
- 基因别名:CD4
- 基因描述:Homo sapiens CD4 molecule (CD4), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:840
- 翻译后氨基酸长度:279
- TranscriptVariant:This variant (2) uses an alternate splice site, lacks two consecutive exons and initiates translation from an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.
- 基因简介:This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
- 规格:10ul 质粒
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