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- accession：NM_145693
- 基因别名：LPIN1
- 基因描述：Homo sapiens lipin 1 (LPIN1), transcript variant 1, mRNA.
- 载体： 现货载体
- CDS区长度：2673
- 翻译后氨基酸长度：890
- TranscriptVariant：This variant (1) encodes the 890 aa isoform (1; also known as alpha) that was described earliest in published descriptions of this human gene.
- 基因简介：This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
- 载体信息：自有图片地址
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
