- accession:NM_001127896
- 基因别名:CHST8
- 基因描述:Homo sapiens carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 (CHST8), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1275
- 翻译后氨基酸长度:424
- TranscriptVariant:This variant (1) represents the predominant transcript. Variants 1-3 encode the same protein.
- 基因简介:The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
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