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- accession：NM_001135769
- 基因别名：PVR
- 基因描述：Homo sapiens poliovirus receptor (PVR), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1095
- 翻译后氨基酸长度：364
- TranscriptVariant：This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (gamma) lacks an internal segment including the putative transmembrane domain, compared to isoform alpha, resulting in its secretion into serum and cerebrospinal fluid.
- 基因简介：The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
