- accession:NM_000373
- 基因别名:UMPS
- 基因描述:Homo sapiens uridine monophosphate synthetase (UMPS), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1443
- 翻译后氨基酸长度:480
- TranscriptVariant:This variant (1) encodes the functional protein.
- 基因简介:This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列