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人UMPS(NM_000373)ORF克隆
人UMPS(NM_000373)ORF克隆
  • 商品货号:FO106037
  • 已售 9 件 | 评价 0 人次 | 关注度 484
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    • accession:NM_000373
    • 基因别名:UMPS
    • 基因描述:Homo sapiens uridine monophosphate synthetase (UMPS), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:1443
    • 翻译后氨基酸长度:480
    • TranscriptVariant:This variant (1) encodes the functional protein.
    • 基因简介:This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列