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- accession：NM_001160008
- 基因别名：NRG1
- 基因描述：Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2b, mRNA.
- 载体：现货载体
- CDS区长度：1263
- 翻译后氨基酸长度：420
- TranscriptVariant：This variant (HRG-beta2b) lacks an internal exon and the 3' exon, but has an alternate 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-beta2b) lacks an internal segment and is C-terminal truncated, compared to isoform HRG-beta1.
- 基因简介：The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq, May 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
