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- accession：NM_022977
- 基因别名：ACSL4
- 基因描述：Homo sapiens acyl-CoA synthetase long-chain family member 4 (ACSL4), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：2136
- 翻译后氨基酸长度：711
- TranscriptVariant：This variant (2) has an additional segment in the 5' region, which introduces an earlier in-frame start codon, as compared to variant 1. The resulting isoform (2) has a 41 aa longer hydrophobic N-terminus, which may impact localization, as compared to isoform 1.
- 基因简介：The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
