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- accession：NM_001270771
- 基因别名：SORBS2
- 基因描述：Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 9, mRNA.
- 载体：现货载体
- CDS区长度：3603
- 翻译后氨基酸长度：1200
- TranscriptVariant：This variant (9) originates from an alternate promoter, has a different 5' UTR, and several in-frame differences in the coding region compared to variant 1, which results in a longer isoform (7) compared to isoform 1.
- 基因简介：Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
